In-Block Derivatization of Herbicidal Carboxylic Acids by Pentafluorobenzyl Bromide
| Autor: | David H. Tompkins, Kadum Ali, Alan P. Thio, Milton J. Kornet |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
chemistry.chemical_classification
Chromatography Carboxylic acid Biochemistry (medical) Clinical Biochemistry Biochemistry Analytical Chemistry chemistry.chemical_compound Electron capture detector chemistry Yield (chemistry) Electrochemistry Acetone Organic chemistry Phenols Gas chromatography Derivatization Triethylamine Spectroscopy |
| Zdroj: | Analytical Letters. 21:477-489 |
| ISSN: | 1532-236X 0003-2719 |
| DOI: | 10.1080/00032718808066339 |
| Popis: | Herbicidal carboxylic acids were analyzed via ECD gas chromatography of their pentafluorobenzyl esters. The derivatives were formed by direct injection of a mixture of the acids and pentafluorobenzyl bromide in acetone; yields showed marked dependence on pKa of the acids. Carboxylic acids which have pKa values greater than 4.5 yielded the corresponding derivatives in poor yield unless triethylamine is included in the mixture. The procedure is fast and particularly convenient for low-level screening, identification and analysis of highly acidic chlorobenzoic, chlorophenoxyalkanoic, and arylacetic acids in the presence of less acidic carboxylic acids and phenols. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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