Sinonasal quality of life after endoscopic resection of malignant sinonasal and skull base tumors

Autor: Steven G. Brooks, Arjun K. Parasher, James N. Palmer, Alan D. Workman, Nithin D. Adappa, Justina L. Lambert, Jordan T. Glicksman, Jenna E. Bergman
Rok vydání: 2017
Předmět:
Zdroj: The Laryngoscope. 128:789-793
ISSN: 0023-852X
DOI: 10.1002/lary.26833
Popis: Objectives Improvement in sinonasal quality of life (QoL) following sinus surgery has been well-documented across the literature. To our knowledge, only one series has evaluated long-term QoL in patients undergoing tumor resection, and that study demonstrated no improvement in rhinologic QoL following malignant tumor resection at 2-year follow-up. The objective of the present study was to evaluate QoL in the 2 years following endoscopic malignant tumor resection. Methods A prospective cohort study was performed, including patients with both malignant and benign sinonasal tumors in a tertiary academic medical center. Patients undergoing endoscopic tumor resection who had completed Sinonasal Outcome Test 22 (SNOT-22) questionnaires were included in the cohort. SNOT-22 questionnaires were administered preoperatively and over a 2-year follow-up period at clinic visits. Longitudinal linear mixed-effects regression was used to compare preoperative QoL to QoL over the 2 years following surgery. Results Among 145 patients included in this study, 64 had malignant tumors. There was a statistically significant improvement in SNOT-22 score from baseline to 2 years for patients with both malignant tumors (37.0, 95% confidence Interval [CI] 32.0–42.1 at baseline; 26.5 95% CI 20.8–32.2 at 2 years; P
Databáze: OpenAIRE
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