Preparation and evaluation of cellulose nanospheres containing 5-fluorouracil
Autor: | B.D. Miglani, G. Mukherji, R.S.R. Murthy |
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Rok vydání: | 1990 |
Předmět: | |
Zdroj: | International Journal of Pharmaceutics. 65:1-5 |
ISSN: | 0378-5173 |
DOI: | 10.1016/0378-5173(90)90002-l |
Popis: | Cellulose derivatives have been used to prepare nanospheres (NS) entrapping the drug, 5-fluorouracil (5-FU). Adopting the technique of desolvation for nanosphere formation and drying via a modified procedure, distinct spheres have been obtained, as observed by scanning electron microscopy. Investigation of the in vivo distribution showed a high concentration of the drug in lung tissue. |
Databáze: | OpenAIRE |
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