Annurca (Malus pumilaMiller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial
| Autor: | Maria D'Avino, Giuseppe Buonomo, Emanuela D'Urso, Ettore Novellino, Domenico Caruso, Gian Carlo Tenore, Luciana Marinelli, Pietro Campiglia |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Malus Normal diet 030204 cardiovascular system & hematology law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Animal science Randomized controlled trial Plasma cholesterol Functional food law Botany Medicine Cultivar Risk factor 030109 nutrition & dietetics Nutrition and Dietetics biology business.industry Cholesterol biology.organism_classification chemistry business Agronomy and Crop Science Food Science Biotechnology |
| Zdroj: | Journal of the Science of Food and Agriculture. 97:2107-2115 |
| ISSN: | 0022-5142 |
| DOI: | 10.1002/jsfa.8016 |
| Popis: | Recent human studies have evaluated the effect of daily apple consumption on plasma cholesterol level, which is recognized as an important risk factor for cardiovascular disease (CVD). Nevertheless, slightly significant effects have been generally registered although consuming more than two apples a day for several weeks.; Results: This study describes the influence of daily consumption of Annurca apples on the cholesterol levels of mildly hypercholesterolaemic healthy subjects. A monocentric, randomized, parallel-group, placebo-controlled, 4-month study was conducted. The subjects (n = 250) were randomly assigned to five treatment groups (each one of 50 subjects: 28 men and 22 women). Four groups were administered one apple per day among the following: Red Delicious, Granny Smith, Fuji, Golden Delicious. The fifth group was asked to consume two Annurca apples per day, since the weight of this cultivar is on average half that of the commercial ones considered in this study. Comparing results, Annurca led to the most significant outcome, allowing a reduction in total and low-density lipoprotein cholesterol levels by 8.3% and 14.5%, respectively, and an increase in high-density lipoprotein cholesterol levels by 15.2% (all P < 0.001).; Conclusion: Our data would reasonably indicate Annurca apple as a useful tool to contribute to the prevention of CVD risk through normal diet. © 2016 Society of Chemical Industry.; © 2016 Society of Chemical Industry. |
| Databáze: | OpenAIRE |
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