Comparison of high-resolution and tandem mass spectrometry for the analysis of nerve agent metabolites in urine

Autor:	Leigh L. Swaim, William Bragg, Rebecca L. Shaner, Elizabeth I. Hamelin, Rudolph C. Johnson
Rok vydání:	2013
Předmět:	Sarin Chromatography Organic Chemistry Russian-VX Cyclosarin Urine Mass spectrometry Tandem mass spectrometry Analytical Chemistry chemistry.chemical_compound chemistry Soman medicine Spectroscopy Nerve agent medicine.drug
Zdroj:	Rapid Communications in Mass Spectrometry. 27:1697-1704
ISSN:	0951-4198
Popis:	Rationale Although use is prohibited, concerns remain for human exposure to nerve agents during decommissioning, research, and warfare. High-resolution mass spectrometry (HRMS) was compared to tandem mass spectrometry (MS/MS) analysis for the quantitation of five urinary metabolites specific to VX, Russian VX, soman, sarin and cyclosarin nerve agents. The HRMS method was further evaluated for qualitative screening of metabolites not included in the test panel.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7103b33a86b4b3cef39d40f741721b7d https://doi.org/10.1002/rcm.6621 Zobrazit plný text záznamu Plný text