Copper-Containing Nanosystems Based on Macromolecular Hydrophilic Stabilizers

Autor: L. N. Borovikova, Yu. I. Zolotova, S. V. Valueva, Olga V. Nazarova, M. E. Vylegzhanina, E. F. Panarin
Rok vydání: 2019
Předmět:
Zdroj: Doklady Chemistry. 489:264-266
ISSN: 1608-3113
0012-5008
DOI: 10.1134/s0012500819110065
Popis: An original method for the synthesis of copper-containing nanosystems for biomedical applications using hydrazine hydrate as a reducing agent was developed. The process involves intermediate formation of the [Cu(NH3)4]2+ complex ion, which ensures the formation of Cu0 nanoparticles without oxide impurity. The 2-deoxy-2-methacrylamido-D-glucose copolymer with 2-(dimethylamino)ethyl methacrylate or bovine serum albumin was used as a macromolecular hydrophilic stabilizer. The spectral and structure-morphological characteristics of the nanosystems were studied. This stabilization resulted in an almost unimodal distribution of zerovalent copper nanoparticles in aqueous solutions due to their rather good shielding by macromolecules.
Databáze: OpenAIRE
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