Antibiotic Encapsulated Nanomaterials with Application in Medical Area
| Autor: | Geta Mitrea, Alina Costina Luca, Elena Ariela Banu, Letitia Doina Duceac, Daniela Luminita Ichim, Madalina Irina Ciuhodaru, Alin Constantin Iordache, Ginel Baciu |
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| Rok vydání: | 2018 |
| Předmět: |
Materials science
Polymers and Plastics medicine.drug_class Antibiotics Nanotechnology 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Nanomaterials Mechanics of Materials Materials Chemistry medicine 0210 nano-technology |
| Zdroj: | Materiale Plastice. 55:552-554 |
| ISSN: | 2668-8220 0025-5289 |
| DOI: | 10.37358/mp.18.4.5072 |
| Popis: | Novel materials belonging to the class of anionic clays are synthesized by investigating their properties at nano scale. Thus, hydrotalcites or layered double hydroxides (LDHs) were used as drug delivery carriers in order to prevent or to treat infections produced by some pathogen agents. Their physical and chemical properties allow them to include different molecules in the interlayer space and then to ensure their transport to the target. The current work reveals the obtaining of nanohybrid compounds type amoxicillin/clavulanic acid-layered double hydroxides (Amox/CA-LDHs) followed by structural and morphological characterization of these nanostructures for future applications as drug controlled release systems. IR spectroscopy and Scanning Electron Microscopy pointed out LDHs ability to incorporate the medicines without modification of therapeutic activity. |
| Databáze: | OpenAIRE |
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