Popis: |
Biologic mesh was developed to address the shortcomings of permanent synthetic mesh, such as chronic inflammation and foreign body reaction, stiffness, and mesh infection. Since the introduction of biologic prosthetics, the market has been rife with new biologic materials attached to largely unsupported claims of superiority and safety. Although the status of literature on biologic mesh is improving, the current data are comprised mainly from animal studies and level III evidence. Over the last decade, surgeons have utilized biologic mesh in a variety of cases including primary and recurrent hernia repair, hernia prophylaxis, and the most widely used application, hernia repair in the contaminated field. The following chapter will review the origin, structure, and mechanics of biologic mesh and conclude with the current indications and shortcomings of biologic prosthetics. |