| Popis: |
The solubility method was used to study the solubilization of nitrofurazone, Uvinul D-50 and Uvinul N-35 in aqueous nonionic surfactant solutions. Enhancement of solubilization with increase in temperature was observed. The solubility of each solubilizate in buffered surfactant solutions maintained a linear relationship with the molar surfactant concentration. The standard free energy change, ΔGso, was negative for all systems, indicating spontaneous solubilization, and increased slightly with increasing hydrophilic chain length. However, ΔGso was essentially independent of temperature. Measurements of the molecular extinction coefficient in nonionic surfactant solution suggest that the value of the molecular extinction coefficient of nitrofurazone at both 260 and 375 nm was always greater than that of UV absorbers. |
