Preparation of optically active secondary alcohols by combination of enzymatic hydrolysis and chemical transformation

Autor:	Takeaki Umemura, Hidenori Danda, Toshio Nagatomi, Akira Maehara
Rok vydání:	1991
Předmět:	Chemical transformation genetic structures Chemistry Organic Chemistry Triacylglycerol lipase Biochemistry eye diseases Hydrolysis chemistry.chemical_compound Enzymatic hydrolysis Nitration Drug Discovery Organic chemistry Mitsunobu reaction sense organs Aliphatic compound Enone
Zdroj:	Tetrahedron. 47:8701-8716
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(01)96192-7
Popis:	Several kinds of optically active secondary alcohols (S)-2, which are important intermediates of bioactive compounds, were prepared from the corresponding racemic acetate (±)-1 in high chemical and optical yields by combination of enzymatic hydrolysis and chemical transformation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::70c13dc2b255d618f0c7d24489afea1a https://doi.org/10.1016/s0040-4020(01)96192-7 Zobrazit plný text záznamu