Toxicopathological effects of siddha drug thamira kattu chendooram in Wistar rats

Autor:	K. Sukumar, R. Madheswaran, Palani Srinivasan, S. Kathirvel, C. Balachandran, T. Lakshmi Kantham, G.A. Balasubramaniam
Rok vydání:	2020
Předmět:	Drug medicine.medical_specialty business.industry Magnesium media_common.quotation_subject Cell volume Albumin Physiology chemistry.chemical_element chemistry Toxicity Siddha medicine Dose group Histopathology business media_common
Zdroj:	Indian Journal of Veterinary Pathology. 44:132-135
ISSN:	0973-970X 0250-4758
DOI:	10.5958/0973-970x.2020.00027.9
Popis:	A 28-day repeated dose toxicity study was conducted to evaluate the toxicity of thamira kattu chendooram (TKC) in Wistar rats. Thirty two male rats were randomly distributed eight each into four groups of control, low, mid and high dose. Rats were treated with different doses of TKC for 28 days. Reduced body weight and feed consumption were noticed in the mid and high dose groups. Blood samples were collected for haemato-biochemical analysis at the end of the study. Haematological parameters revealed decreased total erythrocyte count, haemoglobin and packed cell volume in high dose group. Alterations of serum biochemical values were noticed in glucose, total protein, albumin and magnesium. Gross and histopathological examinations did not reveal any treatment related changes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::70be68feeaf975ab1b8d0bd308098249 https://doi.org/10.5958/0973-970x.2020.00027.9 Zobrazit plný text záznamu