Blood clot method of immunization with observations on pneumococcus toxemia
| Autor: | Francis B. Grinnell, Hans Zinsser |
|---|---|
| Rok vydání: | 1925 |
| Předmět: | |
| Zdroj: | Experimental Biology and Medicine. 23:205-208 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-23-2892 |
| Popis: | Recent work in scarlet fever and the staphylococcus toxin work of J. T. Parker1 have obviously suggested renewed inquiry into pneumococcus infections by similar methods. One of us discussed this in a paper of last June.2 The thought has surely come to many bacteriologists. Moreover, it has been tried many times before; by the Klemperers,3 by Mosny,4 by Tizzoni and Panichi,5 and, particularly, by Wadsworth,6 who discussed the differences between the antitoxic effects of sera produced with culture filtrates and the antibacterial action of those produced with the whole bacteria. Thomas and Frederick Parker,7 furthermore, pointed out microscopic necrosis in various organs not associated with the local presence of pneumococcus.Savchenko's8 papers of 1905 and the Dick studies show that a bacterial substance, poisonous for man and antigenic, may be relatively harmless for all the ordinary laboratory animals; and from J. T. Parker's work we learn that the toxicity and antigenic effectiveness of some poisons may b... |
| Databáze: | OpenAIRE |
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