| Popis: |
Treatment for neurological diseases or trauma remains the last frontier in modern medicine because there is no effective way to repair the central nervous system (CNS) and restore function. In this chapter, we discuss neural stem cells (NSCs) as an important research tool and potential therapy. The chapter begins with a quick review of the derivation of NSCs from the CNS and human pluripotent stem cells. The chapter then progresses to review some of the NSC transplantation work that has been performed in various preclinical animal models of disease and trauma, including stroke, Parkinson disease, amyotrophic lateral sclerosis, and spinal cord injury. We conclude the chapter with a discussion on the future applications of regenerative medicine in psychiatric diseases. |
