Ullmann CO coupling of sterically hindered secondary alcohols using excess amount of strongly coordinating monodentate ligands

Autor:	Yoshitaka Kino, Hayato Sugata, Hiromi Uchiro, Tetsu Tsubogo
Rok vydání:	2017
Předmět:	Steric effects Denticity 010405 organic chemistry Chemistry Organic Chemistry 010402 general chemistry Photochemistry 01 natural sciences Biochemistry Coupling reaction 0104 chemical sciences Coupling (electronics) Aliphatic alcohol Drug Discovery Polymer chemistry Copper catalyzed
Zdroj:	Tetrahedron Letters. 58:1015-1019
ISSN:	0040-4039
Popis:	A new effective copper catalyzed C O coupling reaction using excess amount of strongly coordinating monodentate ligands was successfully developed. Among the DMAP-type monodentate ligands, 4-pyrrolidinopyridine afforded the best results. The developed reaction is widely applicable for the synthesis of various hindered or acyclic secondary alkyl-aryl ethers. In this study, a novel and remarkable acceleration of the coupling reaction using excess amount of monodentate ligands was discovered.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::707e617e4e7a40a09fb210ed388ed504 https://doi.org/10.1016/j.tetlet.2017.01.095 Zobrazit plný text záznamu Full Text from ScienceDirect