Immunoaffinity nanogold coupled with direct analysis in real time (DART) mass spectrometry for analytical toxicology
| Autor: | A. N. Quinto, Kenyon Evans-Nguyen, Tiffanie L. Hargraves |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Dart
Chromatography Chemistry General Chemical Engineering 010401 analytical chemistry General Engineering Analytical chemistry 010402 general chemistry Mass spectrometry 01 natural sciences DART ion source 0104 chemical sciences Analytical Chemistry Analytical Toxicology Drug identification computer computer.programming_language |
| Zdroj: | Analytical Methods. 9:4954-4957 |
| ISSN: | 1759-9679 1759-9660 |
| Popis: | A rapid, definitive trace drug identification technique using nanogold surfaces with mass spectrometry was developed. High-surface area nanogold was deposited on gold wires and functionalized with antibodies. Effective drug capture in toxicological matrices with detection using LC-MS/MS and DART-MS/MS was demonstrated. |
| Databáze: | OpenAIRE |
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