Studies on the synthesis of analgesics. Part 51. Synthesis of 4-(1-oxo-2-isoindolinyl)phenyl derivatives. [Studies on the syntheses of heterocyclic compounds. Part 779]

Autor:	Haruhide Ishimaru, Nakamura Toshihisa, Tetsuji Kametani, Mineharu Hiiragi, Kazuo Kigasawa, Keiko Shirayama
Rok vydání:	1979
Předmět:	chemistry.chemical_compound Butyramide chemistry Organic Chemistry Phenylbutazone medicine Medicinal chemistry medicine.drug
Zdroj:	Journal of Heterocyclic Chemistry. 16:581-584
ISSN:	1943-5193 0022-152X
DOI:	10.1002/jhet.5570160335
Popis:	In order to examine their effect on carrageenin-induced edema in rats, 4-(1-oxo-2-isoindolinyl)-phenyl derivatives were synthesized. 2-Hydroxy-3-[4-(1-oxo-2-isoindolinyl)phenyl]butyramide was found to be more effective than phenylbutazone.
Databáze:	OpenAIRE
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