Acute systemic, splanchnic and renal haemodynamic changes induced by molecular adsorbent recirculating system (MARS) treatment in patients with end-stage cirrhosis

Autor: G. DONATI, F. PISCAGLIA, L. COLÌ, E. SILVAGNI, R. RIGHINI, P. PINI, S. STEFONI, L. BOLONDI
Rok vydání: 2007
Předmět:
Zdroj: Alimentary Pharmacology & Therapeutics. 26:717-726
ISSN: 1365-2036
0269-2813
DOI: 10.1111/j.1365-2036.2007.03420.x
Popis: Summary Aim To evaluate the acute effect of treatment with the molecular adsorbent recirculating system (MARS) on splanchnic, renal and systemic haemodynamics in patients with end-stage cirrhosis. Methods Twelve patients with end-stage cirrhosis, undergoing MARS treatment, were enrolled. The following haemodynamic parameters were measured by means of Doppler ultrasonography and thoracic electrical bioimpedance, before and after each session: portal velocity, renal and splenic resistance indices, cardiac output, cardiac stroke volume, heart rate, mean arterial pressure, systemic vascular resistance. Results Median portal velocity increased significantly after treatment (23.7 vs. 20.3 cm/s, P
Databáze: OpenAIRE
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