A novel solid phase extraction sample preparation method for sensitively determining doxepin and N-nordoxepin in human plasma and its application in a bioequivalence study in healthy Chinese volunteers
| Autor: | Binjie Zheng, Lulu Chen, Tiandong Zheng, Liping Hou, Xinyi Huang, Chao Li, Xintong Wang, Qing Fang, Jie Chen, Zhi Tang, Zhenyu Li, Dongsheng Ouyang |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Analytical Methods. 14:2168-2178 |
| ISSN: | 1759-9679 1759-9660 |
| DOI: | 10.1039/d2ay00129b |
| Popis: | The proposed method not only greatly reduced the complexity of the extraction section, but it was successfully applied to a bioequivalence study of 3 mg of doxepin tablet formulation in 28 healthy Chinese volunteers under fasting and fed conditions. |
| Databáze: | OpenAIRE |
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