A Supramolecular Hydrogel Inspired by Elastin

Autor: Deling Kong, Lei Ding, Ming Tan, Yuehan Hu, Zhimou Yang, Wenjie Wu, Shufang Wang, Cuihong Yang
Rok vydání: 2011
Předmět:
Zdroj: Chinese Journal of Chemistry. 29:2182-2186
ISSN: 1001-604X
DOI: 10.1002/cjoc.201180378
Popis: Self-assembly prevails in nature and learning from nature will lead to biofunctional materials. Inspired by the protein of elastin, we reported in this study on a supramolecular hydrogel bearing the elastin repeating peptide of VPGAG. The visco-elasticity property, morphology of the nanostructures, and aromatic stacking in the self-assembled nanostructure were characterized by a rheometry, transmission electron microscope (TEM), and fluorescence microscope, respectively. The biocompatibility of the gelator was also proved by an MTT assay. Though the supramolecular hydrogel failed to exhibit a high elasticity like elastin, the thixotropic hydrogel might have potentials for the applications in fields of cell culture, controlled-drug release, etc.
Databáze: OpenAIRE