Kawasaki disease preceding haemophagocytic lymphohistiocytosis: Challenges for developing world practitioners
| Autor: | Marc Hendricks, Alan Davidson, Shakti Pillay, John Lawrenson, Rik De Decker |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
endocrine system
Pediatrics medicine.medical_specialty business.industry fungi MEDLINE Gamma globulin Hematology musculoskeletal system medicine.disease Rash Oncology hemic and lymphatic diseases Pediatrics Perinatology and Child Health medicine Kawasaki disease medicine.symptom business hormones hormone substitutes and hormone antagonists Histiocyte |
| Zdroj: | Pediatric Blood & Cancer. 54:1023-1025 |
| ISSN: | 1545-5009 |
| Popis: | Kawasaki disease (KD) is a recognised precipitant of haemophagocytic lymphohistiocytosis (HLH). Although KD has been previously described in the developing world, there are no reported cases of KD preceding HLH. We report a case of a child with a persistent rash and unremitting fever consistent with the diagnosis of KD, who was found to have HLH, after intravenous gamma globulin failed to produce a clinical response. The diagnosis was made using the revised diagnostic criteria for HLH from the Histiocyte Society (1994). She fulfilled six of the eight clinical and laboratory criteria needed to make the diagnosis. |
| Databáze: | OpenAIRE |
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