Popis: |
Stem cells appear to be a novel tool for the regeneration and/or repair of damaged tissues like happen in fistula disease. Randomized controlled studies using stem cells to treat anal fistula has been conducted, and all of them show an excellent safety profile. Nevertheless, the real efficacy is yet hard to assess. That’s the reason why ongoing studies are now running directed to a better define of the most beneficial scenario for stem cell therapy in patients with anal fistula. In this context it is important to remark that with cell therapy, there is no injury to the anal sphincter because tract resection is not required and repeated doses can be used to increase the chance of healing. Importantly, in a clinical setting, fat appears as a great source of stem cells. From this premises, we believe that the stem cells will fulfill a clear unmet medical need and will help improve the healing and hence the quality of life of patients with anal fistula. |