Analytical problems encountered in determining aluminum status from hair in controls and hemodialyzed patients

Autor:	F Paolaggi, F Rousselet, L Duhaux, M C de Vernejoul, Philippe Chappuis
Rok vydání:	1988
Předmět:	Single tube medicine.medical_specialty Chromatography biology Chemistry Biochemistry (medical) Clinical Biochemistry Hair analysis medicine biology.organism_classification Control subjects Cabello Surgery
Zdroj:	Clinical Chemistry. 34:2253-2255
ISSN:	1530-8561 0009-9147
DOI:	10.1093/clinchem/34.11.2253
Popis:	The problems involved in evaluating aluminum concentrations in hair are reviewed, especially those concerning removal of contaminating metals, a critical factor. In the few published studies of Al concentrations in hair, acetone was usually used for its removal. Here, its use in the washing sequence was found to give less precise results and higher Al values than the use of isopropanol. With isopropanol, the whole analysis can be done in a single tube. We compared results with those in the literature. We found that the Al concentration in the hair of control subjects was not related to sex or hair color and that there was a highly significant (P less than 0.001) difference between values for control subjects and hemodialyzed patients: 126 (SD 58) nmol/g, n = 49, vs 226 (SD 104) nmol/g, n = 39, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6ff0fa47757724302923c4e599831858 https://doi.org/10.1093/clinchem/34.11.2253 Zobrazit plný text záznamu