Specific inhibitors of methane oxidation in Methylosinus trichosporium

Autor: Alan W. Thomson, John F. Wilkinson, John H. Hubley
Rok vydání: 1975
Předmět:
Zdroj: Archives of Microbiology. 102:199-202
ISSN: 1432-072X
0302-8933
Popis: Methane oxidation by washed cell suspensions of Methylosinus trichosporium OB3B was selectively inhibited by 25 compounds, including metal binding components such as carbon monoxide (85% O2: 15% CO), KCN (10-6 M), αα′-dipyridyl (10-4 M), 8-quinolinol (10-4 M), thiosemicarbazide (10-5 M), thiourea (10-5 M), hydroxylamine (10-4 M), histidine (10-2 M), British Anti-Lewisite (5x10-3 M), and miscellaneous known inhibitors of other oxygenases. A role for copper in the methane oxygenase system was suggested by the pattern of inhibition and relief of inhibition by added metal ions.
Databáze: OpenAIRE