Specific inhibitors of methane oxidation in Methylosinus trichosporium
Autor: | Alan W. Thomson, John F. Wilkinson, John H. Hubley |
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Rok vydání: | 1975 |
Předmět: | |
Zdroj: | Archives of Microbiology. 102:199-202 |
ISSN: | 1432-072X 0302-8933 |
Popis: | Methane oxidation by washed cell suspensions of Methylosinus trichosporium OB3B was selectively inhibited by 25 compounds, including metal binding components such as carbon monoxide (85% O2: 15% CO), KCN (10-6 M), αα′-dipyridyl (10-4 M), 8-quinolinol (10-4 M), thiosemicarbazide (10-5 M), thiourea (10-5 M), hydroxylamine (10-4 M), histidine (10-2 M), British Anti-Lewisite (5x10-3 M), and miscellaneous known inhibitors of other oxygenases. A role for copper in the methane oxygenase system was suggested by the pattern of inhibition and relief of inhibition by added metal ions. |
Databáze: | OpenAIRE |
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