In vitro and in vivo effects of copper on haemocyanin-o2 binding in the shore crab, Carcinus maenas

Autor:	J. P. Truchot, F. Boitel
Rok vydání:	1992
Předmět:	Pharmacology animal structures biology Decapoda Ecology medicine.medical_treatment Immunology Lethal dose chemistry.chemical_element Cooperativity Hemocyanin biology.organism_classification Copper Crustacean chemistry Biochemistry Hemolymph medicine Carcinus maenas
Zdroj:	Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 103:339-343
ISSN:	0306-4492
DOI:	10.1016/0742-8413(92)90018-3
Popis:	1. When added in vitro to crab haemolymph at concentrations of 50 or 100 mg.1 −1 , copper decreased both haemocyanin-O 2 affinity and the cooperativity of O 2 binding. 2. In crabs contaminated by a lethal dose of waterborne copper (2mg.l −1 ), haemolymph total concentration of the metal never reached levels that could affect O 2 binding properties directly. 3. Exogenous copper added in vitro or entering the animal in contaminated water was found for the most part non filterable and thus probably bound to haemolymph proteins.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6fd1c0fd893bdc4038b024fc1fe273f4 https://doi.org/10.1016/0742-8413(92)90018-3 Zobrazit plný text záznamu