Synthesis of Biaryl Derivatives of Spirofurochromanone in Water and Their Anticancer Activity

Autor: Manga Vijjulatha, Dongamanti Ashok, M. Sarasija, N. Sai Krishna, S. Sree Kanth, Someswar Rao Sagurthi, E. V. L. Madhuri, Akkiraju Anjini Gayatri
Rok vydání: 2019
Předmět:
Zdroj: Russian Journal of General Chemistry. 89:2129-2135
ISSN: 1608-3350
1070-3632
Popis: Biaryl derivatives of spirofurochromanones have been synthesised from 4-bromophenyl derivatives of spirofurochromanones upon catalysis by Pd/C in water. Structures of the synthesised compounds are derived from IR, NMR and HRMS spectral data. The compounds have been tested for in vitro cytotoxicity supported by docking studies.
Databáze: OpenAIRE