Short syntheses of the tricyclic indole alkaloids cimitrypazepine and fargesine
Autor: | Ganesh Ghimire, Björn C.G. Söderberg |
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Rok vydání: | 2016 |
Předmět: |
inorganic chemicals
chemistry.chemical_classification Indole test 010405 organic chemistry Stereochemistry Organic Chemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Catalysis chemistry Heck reaction Intramolecular force Drug Discovery Organic chemistry Tricyclic Palladium |
Zdroj: | Tetrahedron Letters. 57:3873-3876 |
ISSN: | 0040-4039 |
DOI: | 10.1016/j.tetlet.2016.07.061 |
Popis: | A short synthetic sequence leading to the tricyclic alkaloids cimitrypazepine and fargesine is reported. An intramolecular Heck reaction and a palladium catalyzed reductive N-heterocyclization are key steps in the synthesis. |
Databáze: | OpenAIRE |
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