Coexistence of diabetes mellitus and insipidus and optic atrophy in two male siblings

Autor:	Robert A. Norum, Alice Baghdassarian, John D. Graber, Gedeon W. Bretz, Barry J. Zacherle, Robert M. Blizzard
Rok vydání:	1970
Předmět:	Chlorpropamide medicine.medical_specialty Pediatrics endocrine system diseases business.industry General Medicine medicine.disease Genetic pathways Atrophy Endocrinology Diabetes mellitus Internal medicine Diabetes insipidus medicine business Transmitted disease medicine.drug Primary optic atrophy
Zdroj:	The American Journal of Medicine. 48:398-403
ISSN:	0002-9343
Popis:	Two male siblings with diabetes mellitus, diabetes insipidus and optic atrophy are described. Chlorpropamide was of value in treating the diabetes insipidus in the one patient tested but refractoriness apparently developed. Lysin-8vasopressin was effective as treatment over a several month period. A review of the literature suggests that diabetes insipidus and mellitus may occur either as coincident diseases without a common genetic pathway or possibly as a genetically transmitted disease. In the latter instance primary optic atrophy also occurs in some instances.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6fce1b77678e2dafdf422e6e4ee53032 https://doi.org/10.1016/0002-9343(70)90071-9 Zobrazit plný text záznamu