Alveolo-capillary Permeability in Human Septic ARDS
| Autor: | B. A. Reid, Albert A. Driedger, R. R. Anderson, William J. Sibbald, Ronald L. Holliday |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Pulmonary and Respiratory Medicine
ARDS biology Respiratory distress medicine.drug_class business.industry Serum albumin Vascular permeability Critical Care and Intensive Care Medicine medicine.disease Methylprednisolone Anesthesia biology.protein medicine Corticosteroid Pulmonary pathology Cardiology and Cardiovascular Medicine business Dexamethasone medicine.drug |
| Zdroj: | Chest. 79:133-142 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.79.2.133 |
| Popis: | High-dose corticosteroid therapy has been advocated as adjunctive therapy in the adult respiratory distress syndrome (ARDS). We evaluated the effect of pharmacologic doses of corticosteroid (methylprednisolone and dexamethasone) on alveolo-capillary permeability in human septic ARDS by examining the change in appearance of intravenously administered iodine 131 ( 131 I) human serum albumin (I-HSA) into broncho-alveolar secretions, before and after corticosteroid administration. Of 19 patients examined, in 14 (group 1) the clearance of I-HSA was reduced by corticosteroid (pre, .204±.08 ml/hr; post, .096 ±•01 ml/hr; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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