Chemical Composition and Antibacterial Activity ofOriganum majoranaL. Essential Oil from the Venezuelan Andes

Autor:	Alfredo Usubillaga, Sulymar Ramos, Gina Meccia, María Eugenia Lucena, Luis B. Rojas
Rok vydání:	2011
Předmět:	Chromatography biology Terpinen-4-ol General Chemistry Origanum Linalyl acetate biology.organism_classification Enterococcus faecalis law.invention chemistry.chemical_compound Column chromatography chemistry law Agar diffusion test Antibacterial activity Essential oil
Zdroj:	Journal of Essential Oil Research. 23:45-49
ISSN:	2163-8152 1041-2905
Popis:	Origanum majorana L. (Lamiaceae) is a plant that is used in gastronomy and natural medicine. The plant material used in this study was collected at San Isidro de Apartaderos, Merida State. A yield of 0.6% of essential oil was obtained by hydro-distillation using a Clevenger trap. The main constituents found were: cis-sabinene hydrate (30.2%), terpinen-4-ol (28.8%), γ-terpinene (7.2%), α-terpineol (6.9%), trans-sabinene hydrate (4.4%), linalyl acetate (3.8%), and α-terpinene (3.6%). The essential oil was also fractionated over a silica gel dry column. Two main fractions were isolated, the first containing 67.6% of cis-sabinene hydrate and the second 72.8% of terpinen-4-ol. The antibacterial activity of the oil was determined using the agar diffusion method and it was found that it was active against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Klebsiella pneumoniae. Antibacterial activity of the fractions obtained by dry column chromatography was also tested. It was found th...
Databáze:	OpenAIRE
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