O106 Trends in the mortality, incidence and disability-adjusted life-years relating to appendicitis in EU15+ countries: an observational study of the Global Burden of Disease database, 1990-2019

Autor: D W Proctor, R Goodall, K Borsky, J D Salciccioli, D C Marshall, K Shanmugarajah, A Mohamed, J Shalhoub
Rok vydání: 2023
Předmět:
Zdroj: British Journal of Surgery. 110
ISSN: 1365-2168
0007-1323
DOI: 10.1093/bjs/znad101.106
Popis: Introduction Acute appendicitis (AA) is the most common abdominal surgical emergency in the world and places a substantial burden on global healthcare systems. Further characterisation of the disease burden in European Union (EU) 15+ countries may help optimise the distribution of healthcare resources. This observational study assessed the trends in incidence and mortality of appendicitis across EU15+ countries between the years 1990 and 2019. Methods Age standardised mortality rates (ASMRs), age standardised incidence rates (ASIRs) and disability adjusted life years (DALYs) data for appendicitis in males and females were extracted from the 2019 Global Burden of Disease (GBD) study. Time trends within the study period were analysed using Joinpoint regression analysis. Results The median ASMRs across EU15+ countries in 2019 were 0.08/100,000 and 0.13/100,000 for females and males, respectively. Between 1990 and 2019 the median percentage change in ASMR was -52.12% for females and -53.18% in males. The median ASIRs in 2019 for females and males were 251/100,000 and 278/100,000, respectively, with a median percentage change of +7.22% for females and +3.78% for males during the observation period. Decreasing trends in DALYs were observed over the 30-year study period, with median percentage changes of -23.57% and -33.81% for females and males, respectively. Conclusion Overall, a general trend of decreasing appendicitis ASMRs was observed across EU15+ countries, despite small overall increases in appendicitis ASIRs. Variations in both diagnostic and management strategies for appendicitis over the study period are likely contributory to the changing trends.
Databáze: OpenAIRE
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