| Popis: |
Using hexafluoroacetone and trifluoropyruvic acid esters as representative examples, the results of investigations on the reactions of polyfluorinated carbonyl compounds with arylamines, cyclic azomethine–enamines, and nitrogen-containing heterocycles are reviewed. For the first time, the peculiarities of the C-oxyalkylation of nitrogen-containing π-systems with polyfluorinated carbonyl compounds are considered systematically. The results on biological assays of the resulting fluorine-containing products of the C-oxyalkylation are presented. The promising routes for further development of this field from the viewpoint of the creation of new biologically active compounds are outlined. |
