Acetylation and Formylation of 3-Ferrocenylpyrroles

Autor:	Štefan Toma, Battsengel Gotov, Eva Solčániová
Rok vydání:	1999
Předmět:	Acylation Acetic anhydride chemistry.chemical_compound chemistry Acetylation Acetyl chloride Moiety Organic chemistry General Chemistry Electrophilic aromatic substitution Medicinal chemistry Formylation Pyrrole
Zdroj:	Collection of Czechoslovak Chemical Communications. 64:99-106
ISSN:	1212-6950 0010-0765
DOI:	10.1135/cccc19990099
Popis:	Acetylations of 3-ferrocenyl-1-methylpyrrole as well as 3-cyano-4-ferrocenylpyrrole and 3-cyano-4-ferrocenyl-1-methylpyrrole were performed. The course of the acylation is highly dependent on the acylation agent, that is acetyl chloride/aluminum chloride (method A), trifluoroacetic anhydride-acetic acid mixture (method B) or acetic anhydride/Sc(OTf)3 (method C). Method A gives the acetylation on ferrocene moiety, method B affords the trifluoroacetylation on pyrrole moiety and method C affords pyrrole moiety acetylation. Vielsmeier-Haack formylation gives the products of substitution on pyrrole moiety.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6f9f8fa3eb97f816d363a2b1288a9425 https://doi.org/10.1135/cccc19990099 Zobrazit plný text záznamu