| Popis: |
When gel and emulsion are mixed to make a dose, it is referred to as an Emulgel. Emulgel is one of the most exciting topical administration systems owing to its dual type of release control mechanism. The fundamental aim of this formulation is to transfer hydrophobic medication to the systemic circulation through the skin. Emulgel are essentially just water-based emulsions that have gone through a gelling process. The dermatological Emulgel is non-staining, water-soluble, emulsifying, thixotropic, simple to spread, easy to remove, thixotropic and environmentally friendly. Penetration enhancers may be used to increase the efficacy of a product. Consequently, it might be a more effective method of delivering topical medications than the current methods in use. It has become clear that Emulgel is an excellent delivery mechanism for hydrophobic compounds. Carbopol 934, a gelling chemical, was used in this study to create calendula oil Emulgel. Essential oils like clove and mentha were utilised to increase penetration. Afterward, the gel formulation was poured over the emulsion and allowed to harden. Rheological tests, spreading coefficient testing, and in vitro release investigations were conducted on Calendula oil topical Emulgel to determine their sun protection factor. Exfoliative cheilitis may be treated with calendula oil Emulgel applied to the skin. |
