THE ARCHITECTURE OF COLLAGENS IN OSTEOPHYTES: A STUDY BY IMMUNOHISTOCHEMISTRY

Autor: Olusola O. A. Oni, T. O. Alonge, P. Rooney
Rok vydání: 1999
Předmět:
Zdroj: Journal of Musculoskeletal Research. :175-181
ISSN: 1793-6497
0218-9577
DOI: 10.1142/s021895779900018x
Popis: The collagen architecture of osteophytes has been investigated by immunolocalization of types I, II, III and X collagens. Types I and III were observed in the superficial layers, type II in the superficial and middle layers and type X at the cartilage-bone junction. This pattern of distribution suggests a "maturation" pathway from precursor cells at the surface to cells transforming into bone at the base. The collagen fibers appear to be oriented horizontally in the superficial layers and vertically in the middle or intermediate layers, thus mimicking the architectural arrangement in normal articular cartilage.
Databáze: OpenAIRE