Focal lesions of the cerebral white matter in patients with arterial hypertension as evidenced by 5-year prospective study

Autor:	P. I. Lukyanenok, V. F. Mordovin, N. L. Afanasyeva, G. V. Semke
Rok vydání:	2004
Předmět:	medicine.medical_specialty Cerebral white matter business.industry Internal medicine Internal Medicine medicine Cardiology In patient Cardiology and Cardiovascular Medicine Prospective cohort study business
Zdroj:	"Arterial’naya Gipertenziya" ("Arterial Hypertension"). 10:23-25
ISSN:	2411-8524 1607-419X
Popis:	Studies were conducted in 58 patients (33 males and 25 females) aged 36 to 59 years who had arterial hypertension. 24-hour blood pressure (BP) monitoring and brain magnetic resonance imaging were performed in all the patients before and 5 years after the studies. Focal cerebral white matter lesions (FCWML) that had been absent before was found to appear in 15 (25%) patients; FCWML showed no changes in 12 (21%) patients. There was an increase in the number of FCWML in 17 (30%). The patients in whom FCWML appeared had significantly higher baseline values of BP and its time indices and, on repeated examination, they had only significantly higher time indices of BP. The findings suggest that arterial hypertension is a factor that enhances the likelihood of GCWML and that the use of 24-hour BP monitoring permits identification of a group of patients having a high risk for their appearance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6f8a7ca7e855f088c8e9fbbb8ace3e93 https://doi.org/10.18705/1607-419x-2004-10-1-23-25 Zobrazit plný text záznamu