Intra-individual variation of serum thyroxin and triiodothyronine in pregnancy

Autor:	W. G. E. Hölzel, W. Deschner
Rok vydání:	1988
Předmět:	medicine.medical_specialty Pregnancy Triiodothyronine Biochemistry (medical) Clinical Biochemistry Radioimmunoassay Biology Intra individual medicine.disease 3rd trimester Endocrinology Internal medicine medicine Gestation Thyroid function
Zdroj:	Clinical Chemistry. 34:2063-2065
ISSN:	1530-8561 0009-9147
DOI:	10.1093/clinchem/34.10.2063
Popis:	The mean concentrations of triiodothyronine (T3) and thyroxin (T4) in serum were increased in pregnancy, the increases for individuals remaining stable for week 16 to week 40 of gestation. For this period biological intra-individual variations of T3 and T4 in serum were estimated and compared with those of non-pregnant women. The average biological intra-individual CVs for T3 and T4 were of the same order for pregnant and non-pregnant women (6.9-8.4%). The ratios of the biological intra-individual CVs to the biological group CVs were 0.5 to 0.6. Individual values were normally distributed. There was no increase of the intra-individual variation with the lapse of time between two consecutively observed values. The estimated average biological intra-individual CVs were used to derive decision-making criteria in monitoring thyroid function during the 2nd and 3rd trimester of gestation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6f89fa49e8c8acfe73fef0b608d7dd1d https://doi.org/10.1093/clinchem/34.10.2063 Zobrazit plný text záznamu