USE OF INTRALESIONAL CORTICOID AND CALCITONIN NASAL SPRAY IN THE TREATMENT OF CENTRAL GIANT CELL GRANULOMA: CASE REPORT
| Autor: | Letícia Maria Correia Pimentel, José Ricardo Mikami, Vilma Leão Barbosa Neta, Eryck Canabarra Ávila, Suellen Fernandes Santana, Elenisa Glaucia Ferreira dos Santos, Camilla Alves de Carvalho |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Crepitus business.industry Radiography Mandible Buccal administration medicine.disease Pathology and Forensic Medicine Surgery Lesion Calcitonin medicine Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Oral Surgery medicine.symptom business Central giant-cell granuloma Calcification |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 130:e230 |
| ISSN: | 2212-4403 |
| Popis: | Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the jaw bones that has the surgical therapy as conventional treatment. This study aimed to report the case of a patient with conservatively treated aggressive CGCG in mandible. A 29-year-old female patient presented a volumetric increase of the buccal and lingual mandible cortices, with hard consistency areas and crepitus compatible with cortical bone destruction. An incisional biopsy was performed and the histopathological examination confirmed the diagnosis. Treatment was initiated with intralesional injection of triamcinolone hexacetonide 25 mg/mL. An increase and partial calcification of the lesion was observed. The use of calcitonin salmon nasal spray (200 IU/d) was introduced for 3 months, after full calcification. The patient remains in radiographic clinical follow-up without evidence of recurrence or growth. The combination of corticosteroids and calcitonin was shown to be effective in treating aggressive CGCG as a conservative alternative to surgical resection. |
| Databáze: | OpenAIRE |
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