HEREDITARY BILATERAL RETINOBLASTOMA, PINEALOMA AND NORMAL CHROMOSOMES

Autor:	Niels Ehlers, Sigvard Kaae, Erling Ratjen, Kirsten Wølch Rasmussen
Rok vydání:	2009
Předmět:	Pathology medicine.medical_specialty Retina Retinoblastoma Pineal region Cancer General Medicine Biology medicine.disease Ophthalmology Prophase medicine.anatomical_structure medicine Pinealoma Bilateral retinoblastoma Chromosome 13
Zdroj:	Acta Ophthalmologica. 61:838-843
ISSN:	1755-375X
DOI:	10.1111/j.1755-3768.1983.tb01465.x
Popis:	We report a boy with bilateral, familial retinoblastoma recognized at the age of 3 months. At the age of 2 1/2 years the patient developed a tumour in the pineal region. Both tumours were successfully treated by radiation. The chromosomes were normal when examined by the prophase technique, in particular there was no deletion of band q 14 of chromosome 13. We consider the simultaneous occurrence of retinoblastoma and pinealoma as more then a pure coincidence, probably a consequence of a generally increased susceptibility to cancer and of the histogenetic similarities of retina and pineal body.
Databáze:	OpenAIRE
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