A Long-Term Follow-up after Treatment with Colloidal Bismuth Subcitrate and Tinidazole

Autor:	A. Miettinen, Merja Ashorn, Tarja Ruuska, Markku Mäki, R. Karikoski
Rok vydání:	1994
Předmět:	medicine.medical_specialty biology business.industry Spirillaceae Gastroenterology Helicobacter pylori biology.organism_classification Tinidazole Discontinuation Serology Bismuth Subcitrate Internal medicine Medicine Gastritis medicine.symptom business medicine.drug Antibacterial agent
Zdroj:	Scandinavian Journal of Gastroenterology. 29:203-208
ISSN:	1502-7708 0036-5521
DOI:	10.3109/00365529409090464
Popis:	Ashorn M, Ruuska T, Karikoski R, Miettinen A, Maki M. Helicobacter pylori gastritis in dyspeptic children. A long-term follow-up after treatment with colloidal bismuth subcitrate and tinidazole. Scand J Gastroenterol 1994;29:203-208.The connection between dyspeptic symptoms and Helicobacter pylori infection was studied prospectively in 21 children treated for verified H. pylori infection with bismuth subcitrate and tinidazole. Gastroscopy with biopsy was performed before and a mean of 4 months after discontinuation of the treatment. A second post-treatment check with determination of H. pylori antibodies and serum pepsinogen 1 level was made a mean of 1.5 years after cessation of treatment. The therapy given cleared the bacteria in 67% of the patients. No significant difference in symptoms was observed between treatment successes and failures. The histopathologic diagnosis of H. pylori infection was accompanied by positive IgG serology in 15 (75%) of the 20 patients tested, and a decrease in antibody leve...
Databáze:	OpenAIRE
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