Niedokrwistość i niedobór żelaza u chorych z niewydolnością serca — postępowanie diagnostyczne i terapeutyczne
| Autor: | Grzegorz Opolski, Krzysztof Ozierański, Piotr Sypień, Agata Tymińska |
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| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Folia Cardiologica. 12:422-430 |
| ISSN: | 2353-7760 2353-7752 |
| DOI: | 10.5603/fc.2017.0077 |
| Popis: | Chronic heart failure (HF) is a growing problem of highly developed countries. The latest guidelines of the European Society of Cardiology (ESC) on HF have stressed the need for diagnosis and treatment of risk factors and comorbidities that aggravate HF course and affect prognosis. Recently, the subject of numerous studies has included anemia and iron deficiency, which are highly prevalent in patients with HF. By definition, anemia is diagnosed at hemoglobin below 13.0 g/dL in men and 12.0 g/dL in women. In the course of HF many factors can lead to the development of anemia. While iron deficiency may occur independently of the presence of anemia, and independently may deteriorate the prognosis of HF patients. According to the ESC guidelines, iron deficiency in patients with HF is reported with serum ferritin below 100 μg/L or ferritin 100–299 μg/L with iron transferrin saturation below 20%. This article discusses the incidence of anemia, causes of its occurrence in HF, the importance of prognosis, as well as diagnostic and therapeutic options. Currently there are several forms of treatment for anemia. However, the only treatment with proven efficacy and safety is intravenous iron supplementation in symptomatic HF patients with reduced left ventricular ejection fraction associated with iron deficiency. |
| Databáze: | OpenAIRE |
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