Progressive Systemic Sclerosis Resulting in Megacolon

Autor: Robert C. Shamberger, Sara E. Kirkham, John L. Crawford
Rok vydání: 1983
Předmět:
Zdroj: JAMA. 250:1063
ISSN: 0098-7484
Popis: THE TERM "scleroderma" retains general usage despite the well-known involvement by this disease of organs other than the skin. Goetz, 1 in 1945, first proposed its replacement by "progressive systemic sclerosis." The gastrointestinal (GI) tract is not spared, and esophageal disease initially seen as dysphagia or reflux is one of its most typical features. Small-intestinal involvement has also received its share of attention of late, with recognition of pseudo-obstruction, malabsorption, and diarrhea as possible manifestations. Characteristic radiological features have been described in the colon, and constipation may be a troublesome complaint in some patients. Rarely, however, does colonic involvement require more than symptomatic treatment. We report a case of progressive systemic sclerosis in which the GI tract was the major site of involvement and in which progressive colonic disease produced megacolon requiring resection, a previously unreported complication, to our knowledge. Report of a Case A 58-year-old man was admitted to
Databáze: OpenAIRE