Fabrication of microfluidic systems in poly(dimethylsiloxane)

Autor:	Janelle R. Anderson, Daniel T. Chiu, George M. Whitesides, Olivier Schueller, J.C. McDonald, David C. Duffy, Hongkai Wu
Rok vydání:	2000
Předmět:	Rapid prototyping Fabrication Silicon Clinical Biochemistry Integrated systems Microfluidics chemistry.chemical_element Nanotechnology Hardware_PERFORMANCEANDRELIABILITY Biochemistry Soft lithography Analytical Chemistry chemistry Etching (microfabrication) Cleanroom Hardware_INTEGRATEDCIRCUITS
Zdroj:	Electrophoresis. 21:27-40
ISSN:	1522-2683 0173-0835
DOI:	10.1002/(sici)1522-2683(20000101)21:1<27::aid-elps27>3.0.co;2-c
Popis:	Microfluidic devices are finding increasing application as analytical systems, biomedical devices, tools for chemistry and biochemistry, and systems for fundamental research. Conventional methods of fabricating microfluidic devices have centered on etching in glass and silicon. Fabrication of microfluidic devices in poly(dimethylsiloxane) (PDMS) by soft lithography provides faster, less expensive routes than these conventional methods to devices that handle aqueous solutions. These soft-lithographic methods are based on rapid prototyping and replica molding and are more accessible to chemists and biologists working under benchtop conditions than are the microelectronics-derived methods because, in soft lithography, devices do not need to be fabricated in a cleanroom. This paper describes devices fabricated in PDMS for separations, patterning of biological and nonbiological material, and components for integrated systems.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6f34f7e2ea71da6392640b72790a981a https://doi.org/10.1002/(sici)1522-2683(20000101)21:1<27::aid-elps27>3.0.co Zobrazit plný text záznamu Plný text