Stably denatured regions in chromosomal DNA from the cdc2 Saccharomyces cerevisiae cell cycle mutant
| Autor: | M N Conrad, C S Newlon |
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| Rok vydání: | 1983 |
| Předmět: | |
| Zdroj: | Molecular and Cellular Biology. 3:1665-1669 |
| ISSN: | 1098-5549 0270-7306 |
| Popis: | DNA isolated from Saccharomyces cerevisiae strains carrying temperature-sensitive mutations in the CDC2 gene after incubation at the restrictive temperature contains multiple stably denatured regions 200 to 700 base pairs long. These regions are probably stabilized by a DNA-binding protein. They are found in both replicated and unreplicated portions of DNA molecules, suggesting that they are not an early stage in the initiation of DNA replication. |
| Databáze: | OpenAIRE |
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