Benign Intracranial Hypertension Secondary to Vitamin a Deficiency in Rat and Man: Reversible Collagenous Obstruction of CSF Outflow by Metabolically Deranged Fibroblasts

Autor:	Norman H. Bass, K. Van Landingham, C. J. Maffeo, A. B. Butler, E. J. Kasarskis, R. N. Johnson
Rok vydání:	1980
Předmět:	Vitamin medicine.medical_specialty Pseudotumor cerebri Retinol Biology medicine.disease Pathophysiology Fat malabsorption Vitamin A deficiency chemistry.chemical_compound Endocrinology Cerebrospinal fluid chemistry Internal medicine medicine Intracranial pressure
Zdroj:	Intracranial Pressure IV ISBN: 9783642675454
DOI:	10.1007/978-3-642-67543-0_119
Popis:	Pseudotumor cerebri or benign intracranial hypertension can result from impaired outflow of newly-formed cerebrospinal fluid (CSF) from functionally deranged arachnoid villi. An infant with a fat malabsorption syndrome accompanied by deficiency of circulating retinol developed sustained intracranial hypertension that responded to Vitamin A (Vit A) replacement. Simulation of this condition in the rat revealed the reversible pathophysiological mechanism for decreased CSF outflow.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6f283857f58b12501074e01162b2b0a3 https://doi.org/10.1007/978-3-642-67543-0_119 Zobrazit plný text záznamu