Hypoxic preconditioning modifies activity of pro- and antioxidant systems in the rat hippocampus

Autor:	S. A. Stroev, M. O. Samoilov, Tatjana Gluschenko, E. I. Tyul’kova, Markku Pelto-Huikko, M. S. Kislin
Rok vydání:	2012
Předmět:	Antioxidant medicine.medical_treatment Clinical Biochemistry Pharmacology Hypoxic preconditioning medicine.disease_cause Biochemistry Lipid peroxidation chemistry.chemical_compound chemistry medicine Molecular Medicine Bioorganic chemistry Hippocampus (mythology) Hypobaric hypoxia Oxidative stress
Zdroj:	Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 6:333-337
ISSN:	1990-7516 1990-7508
DOI:	10.1134/s1990750812040051
Popis:	The effects of repetitive mild hypobaric hypoxic preconditioning on pro- and antioxidant systems in rat hippocampus have been studied. It was found that three-trial preconditioning by mild hypobaric hypoxia (360 mm Hg, 2 h) induced moderate oxidative stress immediately after the last preconditioning trial. In addition, it down regulated the levels of protein antioxidants (Trx-1, Trx-2, Cu,Zn-SOD) and also decreased several lipid peroxidation products 24 h after the preconditioning.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6f085e9df390e2cdea79cf5eb92b837b https://doi.org/10.1134/s1990750812040051 Zobrazit plný text záznamu Full text from SpringerLink