An Isotope Release Cytotoxicity Assay Applicable to Human Tumors: the Use of 111Indium

Autor:	R. Wiltrout, P. Frost, Z. Maciorowski, N.R. Rose
Rok vydání:	1977
Předmět:	Cancer Research Isotope fungi food and beverages General Medicine Biology Pharmacology Human tumor Oncology Biochemistry Labelling Cytotoxic T cell Chelation Cytotoxicity
Zdroj:	Oncology. 34:102-104
ISSN:	1423-0232 0030-2414
DOI:	10.1159/000225200
Popis:	We have demonstrated that human tumors can be labelled efficiently with the 111indium-oxine chelate. Subsequently, this isotope can be released by cytotoxic lymphoid cells. Both natural and induced cytotoxicity can be demonstrated utilizing this isotope release method. Because of the slow spontaneous release of 111indium and its efficient labelling of human tumor cells, this isotope release assay can be utilized in long-term cytotoxic assays in the study of human tumor immunology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6eff2278adef9d4468d5000d57d8ba52 https://doi.org/10.1159/000225200 Zobrazit plný text záznamu