| Autor: |
Xiao Mei Zhang, Ming Yang Zhang, Zai Gang Luo, Xuemei Xu, Kuai He |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Advanced Materials Research. :1112-1115 |
| ISSN: |
1662-8985 |
| Popis: |
Six β-diketo derivatives of mono-substituted calix[4]arene were synthesized as potential HIV-1 integrase inhibitors and evaluated their inhibition to the strand transfer process of HIV-1 integrase. Their structures were characterized by NMR and HRMS. All the title compounds as potential HIV-1 integrase inhibitors proved to be active in the micromolar range (6.7–37.6 μM) on the strand transfer step. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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