Physicochemical properties of microbial antigens and immunoallergic tests

Autor:	Ia L Bul'vakhter, N D Beklemishev, N G Shin, G S Sukhodoeva
Rok vydání:	1978
Předmět:	chemistry.chemical_classification Allergy Chemistry RNA General Medicine medicine.disease Polysaccharide General Biochemistry Genetics and Molecular Biology Microbiology Brucella abortus medicine.anatomical_structure Antigen Immunology medicine Sensitization Soluble antigen Anaphylaxis
Zdroj:	Bulletin of Experimental Biology and Medicine. 85:344-347
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00801354
Popis:	Experiments were conducted on guinea pigs sensitized by the delayed and immediate types of allergy. Different antigens obtained from the strain of Brucella abortus BA-19 were used for sensitization and the resolving action. Comparison of the resolving properties of the corpuscular, soluble (ultrasound treated) antigens and purified protein fractions, polysaccharide and RNA was carried out in the skin reactions of the immediate and delayed type, passive skin anaphylaxis, acute anaphylactic shock, and the Schults-Dale test. Immediate reactions to the purified protein fraction were weaker than those to the whole soluble antigen, by which the animals were sensitized. Polysaccharide and the RNA-fractions proved to be inactive in the allergic reactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6ef3ee02df2edc509dd4fa752d414199 https://doi.org/10.1007/bf00801354 Zobrazit plný text záznamu Full text from SpringerLink