Pattern of hemoglobinopathies in females attending in antenatal clinic with special reference to the role of RBC parameters in beta-thalassemia carrier detection

Autor: Debasis Mukhopadhyay, Arup Chakraborty, Sunita Bagdi, Aparajita Samaddar, Swapan Pathak
Rok vydání: 2022
Předmět:
Zdroj: National Journal of Physiology, Pharmacy and Pharmacology. 12:1
ISSN: 2320-4672
DOI: 10.5455/njppp.2022.12.10510202204112022
Popis: Background: Hemoglobinopathies are the major cause of anemia throughout the world complicating pregnancy outcome. Hence, detection of hemoglobinopathies in antenatal period is of critical importance as it not only predict the possibility of birth of a child with thalassemia but also reduces the complications associated with anemia in pregnancy. Hence, identification of a reliable cost-effective screening method for detection of hemoglobinopathies is of utmost importance. Aims and Objectives: The present study was conducted to evaluate the role of red blood cell (RBC) parameters including hemoglobin (Hb%), RBC count, mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) in detection of thalassemia carriers among healthy antenatal mothers in a tertiary care hospital of Eastern India. Materials and Methods: Venous blood samples were collected from total 1458 antenatal mothers aged 18 years or above with
Databáze: OpenAIRE