Porous CaCO 3 carriers loaded with scintillation nanoparticles and photosensitizer molecules for photodynamic activation
| Autor: | Pavel Maksimchuk, T. N. Tkacheva, Yu. V. Malyukin, K.O. Hubenko, I. A. Borovoy, S. L. Yefimova, I.I. Bespalova, Alexander V. Sorokin, Roman Grynyov, Ganna Grygorova, V.P. Semynozhenko |
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| Rok vydání: | 2018 |
| Předmět: |
Materials science
Doping chemistry.chemical_element 02 engineering and technology General Chemistry Nanosecond 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Photochemistry 01 natural sciences Acceptor 0104 chemical sciences Reaction rate constant Förster resonance energy transfer chemistry Mechanics of Materials General Materials Science Photosensitizer 0210 nano-technology Luminescence Europium |
| Zdroj: | Microporous and Mesoporous Materials. 263:128-134 |
| ISSN: | 1387-1811 |
| Popis: | We report the creation of a novel composition on the base of porous CaCO3 microspheres loaded with both scintillating gadolinium orthovanadate nanoparticles doped with europium ions GdVO4:Eu3+ (VNPs) and Methylene Blue (MB) photosensitizer molecules. It has been shown that upon both UV- and X-ray excitations of VNPs, an excitation energy transfer from VNPs to MB dye molecules takes place that is revealed in the donor VNPs luminescence intensity and lifetime decrease, as well as MB FRET-induced luminescence appearance. The rise time of the acceptor MB luminescence, which follows the donor decay time has been observed that allows distinguishing of nanosecond acceptor emission due to direct acceptor excitation from the much longer-lived sub-millisecond FRET-induced acceptor one. Using the rise time of acceptor luminescence, FRET efficiency (E = 59%) rate constant ( k t = 2.28 · 10 3 s − 1 ) and physical separation of the donor to acceptor within CaCO3 microparticles ( r d a = 2.45 n m ) at the optimal acceptor concentration have been calculated. The efficiency of created CaCO3@VNPs@MB composition in free radical generation has been analyzed. |
| Databáze: | OpenAIRE |
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